Medical Genetics Test Bank Chapter 12 (Multifactorial Inheritance and Common Diseases)

1- Match the following disease with the most appropriate description: *Waardenburg syndrome?





... Answer is C)
2- Match the following disease with the most appropriate description: *Alzheimer disease?





... Answer is D)
3- Match the following disease with the most appropriate description: *Prader-Willi syndrome?





... Answer is A)
4- Match the following disease with the most appropriate description: *Erythroblastosis fetalis?





... Answer is B)
5- Which of the following is most likely to be useful in the prenatal diagnosis of a neural tube defect??





... Answer is D)
6- In which of the following situations would indirect genetic diagnosis be preferred over direct genetic diagnosis??





... Answer is C)
7- Which of the following is not true of familial adenomatous polyposis coli (APC)??





... Answer is A)
8- Which of the following is least likely to be seen in a multifactorial disease??





... Answer is D)
9- For which of the following diseases has genetic screening (at the population level) been most effective??





... Answer is C)
10- Which of the following techniques is the best example of a population screening procedure??





... Answer is B)
11- Familial hypercholesterolemia?





... Answer is E)
12- Cytotoxic ("killer") T lymphocytes?





... Answer is E)
13- B lymphocytes?





... Answer is E)
14- As gene therapy vectors, adenoviruses have the following advantages over retroviruses:?





... Answer is E)
15- Mutations in tumor suppressor genes?





... Answer is E)
16- Which of the following are difficulties associated with somatic cell gene therapy??





... Answer is D)
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